Bernard Pirotte Selected Research

N- n- pentyl- N'- (2- (4'- methylphenylamino)- 5- nitrobenzenesulfonyl)urea

4/2005

In vitro and in vivo pharmacological characterization of BM-613 [N-n-pentyl-N'-[2-(4'-methylphenylamino)-5-nitrobenzenesulfonyl]urea], a novel dual thromboxane synthase inhibitor and thromboxane receptor antagonist.

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Bernard Pirotte Research Topics

Disease

10	Neoplasms (Cancer) 01/2017 - 05/2002
6	Alzheimer Disease (Alzheimer's Disease) 03/2016 - 11/2006
5	Thrombosis (Thrombus) 01/2018 - 05/2004
4	Inflammation (Inflammations) 03/2016 - 05/2002
4	Cognitive Dysfunction 01/2016 - 01/2012
4	Myocardial Infarction 06/2006 - 04/2004
3	Nervous System Diseases (Neurological Disorders) 03/2016 - 01/2009
3	Atherosclerosis 04/2011 - 01/2006
2	Memory Disorders (Memory Loss) 01/2019 - 05/2013
2	Glioma (Gliomas) 01/2017 - 08/2012
2	Pleurisy (Pleuritis) 03/2014 - 10/2009
2	Schizophrenia (Dementia Praecox) 05/2013 - 11/2006
2	Obesity 02/2010 - 11/2006
2	Hyperinsulinism (Hyperinsulinemia) 02/2010 - 11/2002
2	Neoplasm Metastasis (Metastasis) 12/2008 - 01/2006
2	Stroke (Strokes) 06/2006 - 01/2005
2	Asthma (Bronchial Asthma) 01/2006 - 02/2002
1	Chronic Obstructive Pulmonary Disease (COPD) 12/2020
1	Pituitary Neoplasms (Pituitary Adenoma) 01/2020
1	Gigantism 01/2020
1	Hyperplasia 01/2020
1	Carcinogenesis 01/2020
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2018
1	Abdominal Aortic Aneurysm 01/2018
1	Glioblastoma (Glioblastoma Multiforme) 01/2017
1	Hypertension (High Blood Pressure) 03/2016
1	Reperfusion Injury 03/2016
1	Skin Diseases (Skin Disease) 01/2015
1	Netherton Syndrome 01/2015
1	Acute Liver Failure (Fulminant Hepatic Failure) 03/2014
1	Parkinson Disease (Parkinson's Disease) 05/2013
1	Body Weight (Weight, Body) 04/2011
1	Acute Lung Injury 01/2009
1	Lung Injury 01/2009
1	Pneumonia (Pneumonitis) 01/2009
1	Fibrosarcoma 12/2008
1	Prostatic Neoplasms (Prostate Cancer) 11/2006
1	Mental Disorders (Mental Disorder) 11/2006
1	Mood Disorders (Mood Disorder) 11/2006
1	Pre-Eclampsia (Preeclampsia) 01/2006
1	Septic Shock (Toxic Shock Syndrome) 01/2006
1	Pulmonary Embolism 01/2006

Drug/Important Bio-Agent (IBA)

6	ThromboxanesIBA 04/2011 - 02/2002
4	Ionotropic Glutamate ReceptorsIBA 03/2016 - 11/2013
3	AcidsIBA 01/2019 - 12/2008
3	ProstaglandinsIBA 01/2018 - 02/2002
3	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 03/2016 - 11/2006
3	Adenosine Triphosphate (ATP)IBA 11/2006 - 11/2002
3	ferric chlorideIBA 04/2005 - 05/2004
2	LigandsIBA 12/2020 - 01/2009
2	Thromboxane A2 (A2, Thromboxane)IBA 01/2018 - 11/2006
2	Proteins (Proteins, Gene)FDA Link 01/2017 - 11/2006
2	Antineoplastic Agents (Antineoplastics)IBA 01/2017 - 08/2012
2	Urea (Carbamide)FDA LinkGeneric 01/2017 - 05/2004
2	Pharmaceutical PreparationsIBA 01/2017 - 01/2006
2	nimesulide (Aulin)IBA 03/2014 - 05/2006
2	CarrageenanIBA 03/2014 - 10/2009
2	Potassium Channels (Potassium Channel)IBA 08/2012 - 11/2002
2	Glutamic Acid (Glutamate)FDA Link 01/2012 - 11/2006
2	KATP ChannelsIBA 02/2010 - 11/2006
2	Arachidonic Acid (Vitamin F)IBA 06/2006 - 02/2002
2	LeukotrienesIBA 05/2002 - 02/2002
1	SmokeIBA 12/2020
1	ProlactinIBA 01/2020
1	Growth Hormone (Somatotropin)IBA 01/2020
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2020
1	Sirtuin 1IBA 01/2017
1	compound 18IBA 01/2017
1	SirtuinsIBA 01/2017
1	Histones (Histone)IBA 01/2017
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2017
1	BenzopyransIBA 01/2017
1	ReninIBA 03/2016
1	Retinaldehyde (Retinal)IBA 03/2016
1	Kallikreins (Kallikrein)IBA 01/2015
1	matriptaseIBA 01/2015
1	nitrobenzeneIBA 03/2014
1	CholesterolIBA 04/2011
1	Apolipoproteins E (ApoE)IBA 04/2011
1	Phosphotransferases (Kinase)IBA 06/2010
1	Cytostatic AgentsIBA 06/2010
1	Celecoxib (Celebrex)FDA Link 10/2009
1	PPAR gammaIBA 01/2009
1	Pancreatic Elastase (Elastase)IBA 01/2009
1	CoumarinsIBA 01/2009
1	Peptide Hydrolases (Proteases)FDA Link 01/2009
1	EstersIBA 12/2008
1	PotassiumIBA 11/2006
1	AMPA Receptors (AMPA Receptor)IBA 11/2006
1	AntigensIBA 11/2006
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 05/2006
1	N- (2- cyclohexyloxy- 4- nitrophenyl)methanesulfonamideIBA 05/2006
1	Protein Isoforms (Isoforms)IBA 05/2006
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 05/2006
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 05/2006
1	N- n- pentyl- N'- (2- (4'- methylphenylamino)- 5- nitrobenzenesulfonyl)ureaIBA 04/2005
1	DesminIBA 01/2005
1	Biomarkers (Surrogate Marker)IBA 01/2005

Therapy/Procedure

1	Therapeutics 09/2006
1	Chemoprevention 05/2006